Rodolfo Gasser Selected Research

3- bromo- 10- difluoromethyl- 9H- imidazo(1,5- a)(1,2,4)triazolo(1,5- d)(1,4)benzodiazepine

2/2013	Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.
10/2009	The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction.

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Rodolfo Gasser Research Topics

Disease

4	Cognitive Dysfunction 01/2021 - 10/2009
2	Fibrosis (Cirrhosis) 01/2019 - 01/2018
2	Atherosclerosis 01/2018 - 10/2016
2	Human Influenza (Influenza) 01/2017 - 01/2016
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Rheumatoid Arthritis 01/2021
1	Down Syndrome (Down's Syndrome) 01/2021
1	Ischemia 01/2021
1	Intellectual Disability (Idiocy) 01/2021
1	Schizophrenia (Dementia Praecox) 01/2021
1	Hereditary Nephritis (Alport Syndrome) 01/2019
1	Neoplasms (Cancer) 01/2018
1	Herpesviridae Infections (Herpesvirus Infection) 01/2017
1	Insulin Resistance 10/2016
1	Infections 01/2016
1	Necrosis 04/2005
1	Chronic Kidney Failure (Chronic Renal Failure) 06/2003
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2002

Drug/Important Bio-Agent (IBA)

2	Discoidin Domain Receptor 1IBA 01/2019 - 01/2018
2	Antiviral Agents (Antivirals)IBA 01/2017 - 01/2016
2	Neuraminidase (Sialidase)IBA 01/2017 - 01/2016
2	3- bromo- 10- difluoromethyl- 9H- imidazo(1,5- a)(1,2,4)triazolo(1,5- d)(1,4)benzodiazepineIBA 02/2013 - 10/2009
1	lysophosphatidic acidIBA 01/2021
1	basmisanilIBA 01/2021
1	Retinaldehyde (Retinal)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	Antisense OligonucleotidesIBA 01/2019
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018
1	CollagenIBA 01/2018
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	EndonucleasesIBA 01/2017
1	Fatty Acid-Binding ProteinsIBA 10/2016
1	Blood Glucose (Blood Sugar)IBA 10/2016
1	RNA (Ribonucleic Acid)IBA 01/2016
1	Messenger RNA (mRNA)IBA 01/2016
1	VaccinesIBA 01/2016
1	gamma-Aminobutyric Acid (GABA)IBA 02/2013
1	Therapeutic UsesIBA 02/2013
1	RO 4882224IBA 10/2009
1	BenzodiazepinesIBA 10/2009
1	BenzbromaroneIBA 04/2005
1	benzaroneIBA 04/2005
1	Amiodarone (Amiodarona)FDA LinkGeneric 04/2005
1	Uranyl NitrateIBA 06/2003
1	Tolcapone (Tasmar)FDA Link 01/2002

Therapy/Procedure

1	Therapeutics 01/2017